Reverse Thymus Aging Part II

May 15, 2022 Live Longer by Reversing Thymus Aging – Part II The TRIIM (Thymus Regeneration, Immunorestoration and Insulin Mitigation) Trial caused a lot of excitement when it came out. The first study in humans to show a reduction in the most accurate clock of biological age, our epigenetic clock. The 9 volunteers had a 2.5-year reduction… Continue reading Reverse Thymus Aging Part II

Loss of Synapses is the Engine that Drives Cognitive Decline

May 01, 2022 Yale Can Image Your Brain and Define Your Cognitive Function The long-standing sign of Alzheimer’s is a shrunken brain. In fact, brain shrinkage is so common in all of us, that radiologists will often make offhand comments that an older person has mild shrinkage, but within normal limits. We have presumed that… Continue reading Loss of Synapses is the Engine that Drives Cognitive Decline

HDL Cholesterol Relates to Insulin Resistance, and That’s the Heart Disease Engine

April 24, 2022 HDL Cholesterol Relates to Insulin Resistance, and THAT’s the Heart Disease Engine We have known since 1977 that it’s low HDLs that are the real risk of coronary artery disease. What we didn’t realize back in the 1970-90’s was the dimension of insulin resistance overlaid on HDLs. For folks with insulin sensitivity, higher LDLs… Continue reading HDL Cholesterol Relates to Insulin Resistance, and That’s the Heart Disease Engine

Where Do We Get Oxalates From

April 17, 2022 Where Are We Exposed to Oxalates? Last week we learned that oxalates have no role in humans except as a breakdown product of two amino acids. We make about 25 mg a day. Plants, however, use oxalates widely, mostly as poisons to keep themselves from being eaten by other creatures like insects,… Continue reading Where Do We Get Oxalates From

CERAMIDES are the Missing Link Connecting Saturated Fat to Diabetes

April 03, 2022 Ceramides are the Missing Link to Diabetes and Insulin Resistance Who cares? I never heard of ceramides. Why would anyone waste their time worrying about something I can’t even pronounce? Ah, therein lies the truth. This is one of the metabolic keys to how we get sick. Ok, explain! First of all, what… Continue reading CERAMIDES are the Missing Link Connecting Saturated Fat to Diabetes