PQQ - In Mother's Breast Milk for a Reason

PQQ - In Mother's Breast Milk for a Reason

PQQ is an antioxidant found in mother's breast milk. It's also found in a wide variety of foods like spinach, soy, and legumes. It acts like a vitamin in that you can induce a deficiency state which recovers in a dose-dependent fashion.

Why isn't it listed as a vitamin? Well, because it just hasn't been studied that much. When compared to CoQ10, it appears to win. If nature put it in mother's breast milk, there must be a reason. What's this all about?

It all comes down to the electron transport chain and NAD. NAD was the first fuel the first cell that started life on Earth 4 billions years ago. It has to pass electrons to NADH+, and that energy source still powers sirtuin proteins, which groom and care for your chromosomes. David Sinclair has shown that the degradation of sirtuins can be reversed by taking metformin (go figure, but that's why you are on metformin) and then extra NAD to give them their power source. The rest of the cell runs on ATP, a far more efficient source of energy.

NAD also plays a critical role in capturing high-energy electrons and passing them off to various components in the chain which then feed the electrons into the ATP cycle. That's the nugget of the electron transport chain. CoQ10 is the other key electron harvester and conduit between electron transport chain segments.

We know a ton about CoQ10 and consider it central to making fuel for your body to run on. PQQ acts like CoQ10, and maybe even a little better.

If those electrons are impeded in the electron transport chain, they spill out of the mitochondria and cause oxidative stress like a tidal wave. That's what COVID does within 2 hours of infection. And profound fatigue follows. Ditto probably for CIRS and mold disease.

 Ditto also for Chronic Lyme, long Epstein Barr, on and on. It's the mucking up of the electron transport chain that deprives us of fuel so we feel fatigued and tired, brain-fog galore, and frustration that no one knows how to fix us. We can take CoQ10 as a supplement and it's been proven to help with high-energy needing conditions like congestive heart failure. But what to do if it doesn't work or help? That's where PQQ might play a role. Methylene blue also likely is helping in that space.

You see if you improve the electron transport chain and keep those high-energy electrons in the mitochondria, they don't spill out and cause oxidative damage to membranes, thus depleting plasmalogens and further degrading cellular function. It's that delicate nexus of biomechanical energy production that is sitting in the mitochondria and giving us our fuel. PQQ might just be better at repairing it when it's broken. No harm in trying.

www.What will Work for me. I'm obsessed with this topic. Plasmalogen replacement therapy rebuilds broken membranes caused by oxidative stress. That we know and are witnessing every day. But tools to repair the electron transport chain from incoming artillery fire, like COVID and CIRS (mold and Lyme) damaging the mitochondrial electron transport chain are needed. We haven't parsed out all the details, but a mother's breast milk has plasmalogens and PQQ. There just must be a reason. I'm adding PQQ to my armamentarium for folks with extreme fatigue. It's something to try. I'm intrigued by the lack of human detailed studies. The good news is PQQ is safe to try. The hints that it has a vitamin quality to it suggest that we usually get enough but in our ultraprocessed food chain, perhaps we don't.

References: FASEB, Dietary Interven Liver Disease, Biomolecules, MSBiotechnology, Molecular Metabolism, Vetback, Frontiers in Physiology, Redox Biology, WEbMD,

Pop Quiz.

1. What is PQQ?                    Answer: A vital cofactor that captures and passes on electrons. That makes it a potent antioxidant because it becomes oxidized and saves other molecules that were oxidized and damaged by that oxidation.

2. Where is it naturally found?                 Answer: In soy, legumes, spinach, and mother's breast milk.

3. Do we become deficient in PQQ?                  Answer: We may be but its deficiency may be covered by CoQ10, which we also need. CoQ10 has been widely studied. PQQ has not. If deficiency can occur, it may be considered a vitamin.

4. Extra Credit. Why might PQQ play a role in extreme fatigue from COVID or CIRS?                   Answer. Electrons get backed up by toxin mediated blockage of the electron transport chain. They escape out of the mitochondria and make a firestorm of oxidative stress.

5. Is PQQ safe to take as a supplement?                    Answer. Yes. And there are lots of providers trying to hawk it to you.