Statin Rage

September 17, 2018Statin Rage References: QJMPharmacotherapyPharmacotherapyTrans NeurodegenAm J MedATVBScientific AmericanGraveline, You know statins are widely advertised as being good for your heart. And the literature supports that if we look at you as a "walking heart" with little more attached on the outside. Considering that the house of medicine makes the most money off you for heart disease, cardiologists hold a lot of sway over the health care system. Hence, when the heart doctors (aka medical "God") say, "Thus spoketh....., thou shall take statins!" the house of medicine snaps to attention and does so. I'm not here to argue the whole case, just the case of cognitive damage as shown in "statin rage". These are not innocuous drugs, and you are more than just a heart. Your brain might be important too. If you act like a jerk, your love relationships suffer and they might be more important to you than your arteries. What does the literature say about cognitive effects? Quite a lot actually. What caught my attention was a plea from a client who has repeatedly felt terrible anger when exposed to statins. And he is a very high risk for heart disease, and "needs" his statin. Or does he? Is there another way? (Hint: YES!!) I reviewed several studies. The first in Translational Neurodegeneration suggests there are two competing processes going on. They review all the studies of cognitive decline, and find design problems with all the studies: for example, most patients in some studies are on low dose statins whereas high dose is what makes the side effects, and most patients are actually on higher doses. But they end up concluded that there really are some folks who get pretty severe memory issues, and get better when the statin is stopped. They plead that we be aware of those effects and be brave enough to stop the statin if memory issues occur. Just stop! In the QJM study, four patients were found with "manifestations of severe irritability" included homicidal impulses, threats to others, road rage, generation of fear in family members, and damage to property. All got better on stopping the statin, and worse again when it was restarted. Conclusion: be brave enough to stop! There is more. Scientific American has a nice review on memory loss and statins. Duane Graveline, NASA astronaut, lost his memory for the duration of being on statins and wrote a book about it. You might want to read that book if it catches your eye. www. What will work for me. Loss of memory, road rage. How much can you take? These effects may not be common, but they are indications that there is brain damage/effects of taking statins. And published studies in randomized fashion of cognitive ability again show damage, albeit not that commonly. One could ask, just how well do the people selling the drug report of effects that could damage their sales? Only you can answer that one. As for me, I'll change my diet to avoid taking statins. There are other answers that are just as effective. For example, consider Gundry's report at the American Heart meeting just a month ago. Hmmm. Cheaper, better, no side effects.   Pop Quiz
  1. Statins can damage your brain. T or F                                     Answer. True as shown by memory loss, cognitive decline, rage, and mood.......
  2. The only organ that matters in your body is your heart, and as long as you let your heart be the only organ that is talked about, statins are useful. T or F                 Answer: Ok, do you get the irony?
  3. Randomized studies, conducted by the folks selling a product, are likely to be absolutely clear about picking up pervasive, subtle shifts in cognitive ability?       Answer: Can you tell that I'm on a rant here? I'm deeply skeptical about the integrity of our pharmaceutical industry, considering their demonstrated history.
  4. Is there a role for statins?                                                                              Answer: I think there is. Someone who wants to keep eating donuts and ice cream, sugar and white flour, and has had a heart attack, likely needs to be on a statin. Those willing to eat differently and let their lab tests, including their cholesterol, be their guide, there are choices.
  5. How common is statin rage?                                                                 Answer: Rare. It's there, but not common. Many other brain effects. It's a "no brainer". Gotta stop.
   

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