Fast Mimicking Diet 4 Reversing DiabetesMarch 26, 2018
Fast Mimicking Diet 4, Reversing Diabetes
References: Whitehall Study, Circulation, Aging, Diabetes Care, Cell,
This is a big deal. If you read no email this year but this one, you will be well served. The reversal of diabetes is so important, it is a game changer for all of medicine. Why? Two reasons. The first is that it is so destructive, effecitively being the cornerstone for all our diseases of modern society. We have defined diabetes by committee and decided that it really wasn't a disease until you got to a blood level of 124 or so, measured twice, or a Hemoglobin A1c of 6.2 or 6.4 (Remember: the A1c is the percent of hemoglobin molecules with a glucose stuck on them. Red cells live 100 days, about, which makes the A1c a nice surrogate marker for your average glucose over the last 100 days..
But that is looking at a disease you might think about treating. What would happen if you decided to consider what blood sugar results in optimal function? I would refer you to the Whitehall Study from England, It showed that for every point of glucose above 86, you have a 5% increased risk of heart disease. And there is wide acknowledgement now that we need to lower blood sugar, which modern medicine does by treating with drugs. That means an optimal blood sugar should be 86. Bredesen shows abundant evidence that a HgbA1c of 5.5 is what you want if you are anxious about Alzheimer's. The second is that everyone has it. There are all sorts of papers saying how many millions of people have it, but that is the DISEASE.
If you want optimal function, the picture is much gloomier. The simplest explanation of how your body progresses to diabetes is as follows: your fat cells become insulin resistant in relationship to their size. As you get fatter, your fat cells get bigger. You don't make more. And as the fat cells get bigger, insulin receptors get further apart. You become insulin resistant. You raise your insulin to keep that blood sugar in control, which you can only do for so long. After a while, you run out of the ability to keep raising your insulin level.
It's as though you were only given so much insulin in a lifetime. As long as you were only burning a tiny amount a day, you can live a very long time. But it has become pretty apparant that once we get overweight, we are burning up our insulin supply faster than we can maintain for a lifetime of 100 years. And that is what we see today in modern medicine. As we age, being a bit plump gradually turns into our blood sugar slowing rising, and your being put on one pill after another until you get to age 55 or so, and then you flunk out and get put on insulin. Your islets in your pancreas look shaggy with fewer healthier insulin-producing cells. And then your kidneys fail and you get on dialysis, and then you flunk and get Alzheimer's.
Till now, the key to reversing diabetes has all been about losing weight, making fat cells smaller and getting the residual ability you have to make insulin in line with your reserve of insulin producing capacity. Imagine having an insulin level of 35 when you weight 190, but a level of 2 when you weight 132. That's what we see clinically happening. Here is where the Fast Mimicking Diet (FMD) comes in. What would you think if I told you that the FMD turns on the genes that literally wipe out old, dead, decaying tissue and starts rejuvenation of new insulin producing cells? Yes, produces new insulin cells. We have never seen anything quite like this before. This is like the holy grail of medicine, and it's right there in front of our faces. The FMD turns on genes that support resiliency, getting rid of old garbage that's in the way and turning on the growth of new stem cells. This is dieting for your genes sake. And all we are asking of you is 5 days a month until you have got yourself fixed.
WWW.What will work for me. I've been getting older and I have a family history of diabetes. To my alarm, this year my A1c ticked up from it's usual 5.2-5.4. I've already done one cycle. I'm starting cycle number two. I just came back from a trip to see old friends I grew up with in India. I'm going to send them copies of Longo's book. My advice to you is to not trust me, or your own doctor on this topic. Trust your own lab results. Watch your own response. The data is there. This diet will eventually become the "human diet". We will all be on a variation of it. The good news, if you don't have any risk factors, is that you only need to do it twice to three times a year, provided you exercise properly.
- Diabetes starts at a Hemoglobin A1c of 6.2. T or F Answer: true, if you call it as the disease and use current medicine's standards. Optimal is a whole different story. If you have worries about heart disease, Alzheimer's. autoimmune disease.. or just want to age gracefully into your 90s, you want an optimal A1c: below 5.5
- You can lower your A1c by losing weight. How does that work? Answer: your fat cells get smaller and the residual insulin you have left become in line with the amount you need to control those fat cells.
- If I'm getting a little older and a little heftier, what is happening to my insulin producing cells in the islets in my pancreas? Answer: They are getting fewer and making less insulin.
- How many days do I have to do this diet thing? Answer: 5. Four, as best we know, isn't sufficient.
- What is an optimal blood sugar? Answer: Your family doctor will tell you under 100 or so but won't call you diabetic until you are 126, or if they are just checking your urine, you will be normal when you have a sugar below 180 because your kidneys can reabsorb anything below 180. (I kid you not, I talked to a person this week whose doctor was still checking urine for diabetes.)